Spatial Transcriptomics Reveals Inflammation and Trans-differentiation States of Acute Myeloid Leukemia in Extramedullary and Medullary Tissues
Enes Dasdemir, Ivo Veletić, Christopher P. Ly, Andres Ernesto Quesada, Christopher D. Pacheco, Fatima Zahra Jelloul, Pâmella Borges, Sreyashi Basu, Sonali Jindal, Zhiqiang Wang, Alexander J. Lazar, Khalida Wani, Dinler A. Antunes, Patrick Kevin Reville, Preethi H. Gunaratne, , Hussein A. Abbas
This study uses spatial transcriptomics to analyze AML in both medullary and extramedullary tissues, revealing inflammation and trans-differentiation states.
iScience · Nov 29, 2025Peer-reviewedCancer Biology