PDE10A Inhibition Reduces NLRP3 Activation and Pyroptosis in Sepsis and Nerve Injury
Bradford C. Berk, Camila Lage Chávez, Chia George Hsu
This study shows that PDE10A inhibition reduces NLRP3 inflammasome activation and pyroptosis in sepsis and nerve injury models, with potential for clinical application.
International Journal of Molecular Sciences · May 8, 2025Peer-reviewedImmunology