Author

Thomas Holst‐Hansen

University of CopenhagenORCID 0000-0002-5314-7802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Ala TrusinaiD· 2 shared Andrew G. WangiD· 1 shared Aura MuntaselliD· 1 shared Elena Martín AbadiD· 1 shared Jordi García‐OjalvoiD· 1 shared Michael JunkiniD· 1 shared Miguel López‐BotetiD· 1 shared Minjun SoniD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Ala TrusinaORCID

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2 papers

Recent·Most cited

Spatiotemporal NF-κB dynamics encodes the position, amplitude and duration of local immune inputs

Minjun Son, Tino Frank, Thomas Holst‐Hansen, Andrew G. Wang, Michael Junkin, Sara Saheb Kashaf, Ala Trusina, Savaş Tay

The paper shows that NF-κB dynamics in fibroblasts encode cytokine dose, duration, and distance through wave-like propagation, creating spatially defined gene expression zones.

Science Advances · Aug 31, 2022Peer-reviewedSystems Biology

Impact of Zygosity in Bimodal Phenotype Distributions

Thomas Holst‐Hansen, Elena Martín Abad, Aura Muntasell, Miguel López‐Botet, Mogens H. Jensen, Ala Trusina, Jordi García‐Ojalvo

The paper investigates how zygosity affects gene expression in a bimodal distribution by analyzing HCMV-infected donors and using mathematical models to identify feedback mechanisms in gene regulatory circuits.

Biophysical Journal · Jul 1, 2017Peer-reviewedSystems Biology