Ala Trusina

The paper shows that ADIP and Diversin form a mechanosensitive complex involved in planar cell polarity during morphogenesis and wound repair in Xenopus embryos.

This paper uses a computational model to show that pancreatic islets can switch between transient and persistent inflammation modes based on feedback loops and islet size.

The paper uses lineage tracing and mathematical modeling in zebrafish to show that heterogeneous progenitor decisions establish a precise BEC-to-hepatocyte ratio and drive postembryonic liver growth.

The paper shows that NF-κB dynamics in fibroblasts encode cytokine dose, duration, and distance through wave-like propagation, creating spatially defined gene expression zones.

The paper investigates how cell cycle regulation influences transcriptional heterogeneity and lineage priming in embryonic stem cells differentiating into primitive endoderm.

The paper models the NANOG-GATA6-FGF4 network to show how ICM cells can be partitioned into EPI and PE through transient synchronization and FGF4 signaling.

The paper challenges the two-step model of tube formation by showing that either cell intercalation or wedging alone can suffice for the sheet-to-tube transition, supported by simulations of Drosophila, Sea urchin, and mammalian systems.

The paper quantifies the fitness costs and benefits of protein deposit formation via phase separation in yeast, showing environmental and functional demands influence fitness outcomes and generate phenotypic variability.

The paper investigates how zygosity affects gene expression in a bimodal distribution by analyzing HCMV-infected donors and using mathematical models to identify feedback mechanisms in gene regulatory circuits.