Systems BiologyScience AdvancesPeer-reviewed
Spatiotemporal NF-κB dynamics encodes the position, amplitude and duration of local immune inputs
Minjun Son, Tino Frank, Thomas Holst‐Hansen…·Savaş Tay
The paper shows that NF-κB dynamics in fibroblasts encode cytokine dose, duration, and distance through wave-like propagation, creating spatially defined gene expression zones.
46 citations