Evidence from three taxonomically distinct species for a non-AhR mechanism of developmental neurotoxicity of an environmentally derived mixture of polycyclic aromatic hydrocarbons
Samantha Phelps, Melissa Chernick, Javier Huayta, Aliyah S. Webster, Abigail S. Joyce, Kerry Ettinger, Caroline Beggs, Safiatou Zibo, P. Lee Ferguson, Richard T. Di Giulio, Joel N. Meyer, Nishad Jayasundara
This study investigates the neurotoxic effects of a PAH mixture across three species, finding neurotoxicity occurs through a non-AhR mechanism.
bioRxiv · Aug 21, 2026 · PreprintPharmacology & Toxicology