Author

Yuchen Zhang

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metagenomics· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Abigail S. JoyceiD· 1 shared Addison N. Webster· 1 shared Aleyna K. BuyukaksakaliD· 1 shared Ali D. GüleriD· 1 shared Amani Akkoub· 1 shared Arun Karthikeyan· 1 shared Austin B. KeeleriD· 1 shared Christopher D. DeppmanniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Abigail S. JoyceORCID

Author profile →

3 papers

Recent·Most cited

The FERM Guild: A Differentially Correlated Microbial Module Drives Hypertension via Metabolic Flux Perturbations

Wenkai Lai, Yuchen Zhang, Shaoping Huang, Shirong Lai, Fuxin Lin, Ziwei Wang, Shanwen Sun, Fenglong Yang

The paper identifies a microbial module, the FERM guild, associated with hypertension through metabolic flux changes using pFBA and DoubleML.

mSystems · Aug 4, 2026Peer-reviewedBioinformatics

Autoinducer-2 and acyl homoserine lactones have contrasting effects on ammonia and nitrite-oxidizing sludge

Hira Waheed, Yuchen Zhang, Lan Nguyen, Abigail S. Joyce, P. Lee Ferguson, Jeseth Delgado Vela

This study shows that AHLs boost ammonia oxidation while AI-2 suppresses it but enhances nitrite oxidation, suggesting they regulate nitrification differently.

bioRxiv · Jan 8, 2026 · PreprintMicrobiology

A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs

Elizabeth Godschall, Taha Buğra Güngül, Isabelle R. Sajonia, Aleyna K. Buyukaksakal, Orien Dong-Ang Li, Sophia Ogilvie, Austin B. Keeler, Guilian Tian, Omar Koita, Yu Shi, Tyler C J Deutsch, Maisie Crook, YuChen Zhang, Nicholas J. Conley, Addison N. Webster, , Ali D. Güler

This paper shows small-molecule GLP1RAs modulate reward processing via a specific neural circuit in the central amygdala, affecting dopamine release and hedonic feeding.

bioRxiv · Dec 12, 2024 · PreprintNeuroscience