Author

Jeffrey R. Janus

Mayo ClinicORCID 0000-0002-5324-0740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Akhilesh PandeyiD· 2 shared Anguraj SadanandamiD· 2 shared David J. H. F. KnappiD· 2 shared Guruprasad KalthuriD· 2 shared Mark E. ShermaniD· 2 shared Megan L. RittingiD· 2 shared Nagarajan KannaniD· 2 shared Syed Mohammed Musheer AalamiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Akhilesh PandeyORCID

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Author profile →

2 papers

Recent·Most cited

A Rare Multipotent Peg-like Epithelial Cell is a Candidate Cell-of-Origin for High-Grade Serous Ovarian Cancer

Megan L. Ritting, Wenmei Yang, Syed Mohammed Musheer Aalam, Hui Zhao, Feng Liang, Jianning Song, Mihai Gabriel Dumbrava, Wazim Mohammed Ismail, Dong‐Gi Mun, Chunling Hu, Opalina Roy, Keyur Chaludiya, Geng Xian Shi, Daphne Norma Crasta, Kenneth Schaufelberger, , Nagarajan Kannan

The paper identifies a rare multipotent epithelial cell in the fallopian tube as a potential cell-of-origin for high-grade serous ovarian cancer using multi-omic profiling and organoid models.

bioRxiv · Sep 23, 2025 · PreprintCancer Biology

Receptor Tyrosine Kinase Profiling Identifies Chronic Constitutive Floodgate Oxidative Signaling in Glutathione-Independent Human Mammary Luminal Progenitor Cells

Syed Mohammed Musheer Aalam, Megan L. Ritting, Hari PS, Geng‐Xian Shi, Kingsley Shih, Yifei Dong, Guruprasad Kalthur, Miao Cao, Yifan Yu, David J. H. F. Knapp, Peter D. Eirew, Davide Pellacani, Chitra Priya Emperumal, Hequn Wang, Jeffrey R. Janus, , Nagarajan Kannan

This study identifies cKIT as a key mediator of oxidative signaling in human mammary luminal progenitor cells and links its activation to poor outcomes in basal-like breast cancers.

bioRxiv · Jul 15, 2025 · PreprintCancer Biology