Dylan T. Boehm

This study develops a novel transmembrane STING agonist and validates its efficacy in genetically humanized mice, showing enhanced immune and antitumor responses.

This study compares molecular and immune responses to diverse STING agonists to identify differences in potency and immune outcomes.

This study shows that intratumoral mRNA-1273 vaccine injections delay melanoma growth in mice by increasing CD8+ T cell infiltration and enhancing immune checkpoint therapy responses.