Author

Shirley S. L. Lee

German Center for Neurodegenerative DiseasesORCID 0000-0002-5349-8450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adrian PerdyaniD· 1 shared Ayşe UlusoyiD· 1 shared Donato A. Di MonteiD· 1 shared Jakub MieczkowskiiD· 1 shared Jochen H.M. PrehniD· 1 shared Rita Pinto‐CostaiD· 1 shared Sinéad A. O’SullivaniD· 1 shared Urszula ŁawrynowicziD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Adrian PerdyanORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

α-Synuclein impairs mitochondrial function and alters cryptochrome regulation in the substantia nigra

Sinéad A. O’Sullivan, Adrian Perdyan, Ayşe Ulusoy, Rita Pinto‐Costa, Shirley S. L. Lee, Urszula Ławrynowicz, Jochen H.M. Prehn, Jakub Mieczkowski, Donato A. Di Monte

This study shows that α-synuclein accumulation in dopaminergic neurons leads to mitochondrial dysfunction and changes in circadian gene expression, contributing to neuronal damage in Parkinson's disease.

bioRxiv · Aug 21, 2026 · PreprintNeuroscience