Author

Hiroyuki Sasaki

Tokyo University of TechnologyORCID 0000-0002-5358-5853Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hiroyuki Sasaki1 paper · Waseda University

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Hiromi TerasawaiD· 2 shared Kazuaki MondeiD· 2 shared Nami MondeiD· 2 shared Tomohiro SawaiD· 2 shared Wright Andrews Ofotsu AmesimekuiD· 2 shared Yosuke MaedaiD· 2 shared Akatsuki SaitoiD· 1 shared Hirotaka OdeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMicrobiology

Hiromi TerasawaORCID

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2 papers

Recent·Most cited

HIV-1 can undergo Env-independent retrotransposon-like activity

Sojiro Matsumura, Wright Andrews Ofotsu Amesimeku, Samiul Alam Rajib, Nami Monde, Hiroyuki Sasaki, Hiromi Terasawa, Md. Jakir Hossain, Tomohiro Sawa, Yosuke Maeda, Yorifumi Satou, Kazuaki Monde

This study shows HIV-1 can perform reverse transcription and partial integration without Env or infection, suggesting a retrotransposon-like mechanism.

bioRxiv · Apr 21, 2026 · PreprintMicrobiology

Lenacapavir binding to immature Gag triggers the emergence of giant HIV-1 virions

Wright Andrews Ofotsu Amesimeku, Yoshihiro Nakata, Nami Monde, Hiromi Terasawa, Hirotaka Ode, Hiroyuki Sasaki, Takeshi Matsui, Perpetual Nyame, Md Jakir Hossain, Akatsuki Saito, Tomohiro Sawa, Terumasa Ikeda, Yosuke Maeda, Yasumasa Iwatani, Kazuaki Monde

The paper shows lenacapavir binding to immature Gag leads to non-infectious giant HIV-1 virions with altered structure and function.

bioRxiv · Jul 16, 2025 · PreprintMicrobiology