Author

Paul W. Chrystal

University of AlbertaORCID 0000-0002-5371-1178Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Organism:zebrafish· 3 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew Jan WaskiewicziD· 3 shared Curtis R. FrenchiD· 3 shared Ordan J. LehmanniD· 3 shared Serhiy HavryloviD· 2 shared Suey van Baarle· 2 shared Adrián Santos‐LedoiD· 1 shared Ann S. Grosse· 1 shared Ann-Marie PetursoniD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenetics

Andrew Jan WaskiewiczORCID

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4 papers

Recent·Most cited

GeneticsGenesPeer-reviewedJan 26, 2021

The Axenfeld-Rieger syndrome gene FOXC1 contributes to left-right patterning

Paul W. Chrystal, Curtis R. French, Francesca Jean…·Andrew Jan Waskiewicz

This paper shows that FOXC1 mutations in zebrafish cause left-right axis defects and congenital heart defects, similar to human Axenfeld-Rieger syndrome.

8 citations

zebrafishexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintAug 13, 2020

Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling

Serhiy Havrylov, Paul W. Chrystal, Suey van Baarle…·Ordan J. Lehmann

The paper shows that FOXC1 affects ciliation and cilia-dependent signaling, contributing to pleiotropic phenotypes in Axenfeld-Rieger Syndrome.

DOI 10.1101/2020.08.13.249334

mousestatistical model

𝕏 PostBluesky

Developmental BiologybioRxivPreprintFeb 10, 2019

An alternatively spliced zebrafish jnk1a transcript has an essential and non-redundant role in development of the first heart field derived proximal ventricular chamber.

Adrián Santos‐Ledo, Sam J. Washer, Tamil Dhanaseelan…·Bill Chaudhry

DOI 10.1101/546184

zebrafishstatistical model

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 10, 2018

Morphogenesis and differentiation of embryonic vascular smooth muscle cells in zebrafish

Thomas R. Whitesell, Paul W. Chrystal, Jae‐Ryeon Ryu…·Sarah J. Childs

The paper traces the morphogenesis and transcriptome of early vascular smooth muscle cells in zebrafish using foxc1b as a marker.

1 citation

zebrafishbulk RNA-seq

𝕏 PostBluesky