Tatenda L. Chakoma

The paper distinguishes between spontaneous and stimulus-driven acetylcholine dynamics in sensory and prefrontal cortex using genetically encoded sensors and multivariate modeling in awake mice.

This study shows that basal forebrain cholinergic activation modulates amygdala neuron activity based on reward contingency, affecting conditioned behavior but not unconditioned responses.

The paper identifies a functional topography in basal forebrain cholinergic neurons that differentiates their responses to sensory cues and reinforcement outcomes in mice.