Mason Sweat

This study shows that inhibiting miR-200c in adult mice improves heart function and reduces fibrosis after myocardial infarction by reactivating developmental transcription factors.

The paper shows that TBX5 recruits CHD4 to regulate chromatin organization in atrial cardiomyocytes, affecting gene expression and atrial rhythm.

This paper describes a method to generate high-purity, scalable human iPSC-derived cardiomyocytes using a bioreactor, showing improved viability, function, and consistency compared to traditional methods.