Author

Wei Shi

University of North Carolina at Chapel HillORCID 0000-0002-8177-2920Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Wei Shi7 papers · Beihang University

Biology Disciplines

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Developmental Biology· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Frank L. ConloniD· 4 shared Haley A. DaviesiD· 2 shared Ileana M. CristeaiD· 2 shared Lauren K. WassoniD· 2 shared William T. PuiD· 2 shared Xinlei ShengiD· 2 shared Zachary L. RobbeiD· 2 shared Angel P. Scialdone· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersGenomics

Frank L. ConlonORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintDec 4, 2024

CHD4 Interacts With TBX5 to Maintain the Gene Regulatory Network of Postnatal Atrial Cardiomyocytes

Mason Sweat, Wei Shi, Erin M. Keating…·William T. Pu

The paper shows that TBX5 recruits CHD4 to regulate chromatin organization in atrial cardiomyocytes, affecting gene expression and atrial rhythm.

DOI 10.1101/2024.12.04.626894

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 12, 2022

A Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1-mediated Trabeculation Cessation

Wei Shi, Angel P. Scialdone, James I. Emerson…·Frank L. Conlon

This study identifies a CHD4 missense mutation causing ventricular noncompaction by repressing ADAMTS1-mediated trabeculation cessation in mice and humans.

2 citations

mouseexperimental assay

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 28, 2021

CHD4 is recruited by GATA4 and NKX2-5 silencers to repress non-cardiac gene programs in the developing heart

Zachary L. Robbe, Wei Shi, Lauren K. Wasson…·Frank L. Conlon

The paper identifies how CHD4/NuRD is recruited to cardiac gene loci via interactions with GATA4, NKX2-5, and TBX5, revealing its role in repressing non-cardiac gene programs during heart development.

DOI 10.1101/2021.10.28.466285

mouseDNA methylation

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 29, 2020

Cardiac Sex Differences are Established Prior to Gonad Formation

Wei Shi, Xinlei Sheng, Kerry M. Dorr…·Frank L. Conlon

The paper identifies sex-specific transcriptomes and proteomes in cardiac tissue, showing that sex differences are established before gonad formation through post-transcriptional mechanisms and hormonal/sex chromosomal factors.

3 citations

mouseproteomics

𝕏 PostBluesky