Author

Nicolas Carlos Kahn

University Hospital HeidelbergORCID 0000-0002-5403-8069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Agnes W. BootsiD· 2 shared Carmen Veith· 2 shared Christian ConradiD· 2 shared Marc Andre SchneideriD· 2 shared Michael KreuteriD· 2 shared Robert Lorenz ChuaiD· 2 shared Roland EilsiD· 2 shared Bianca P. HennigiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersMolecular Biology

Agnes W. BootsORCID

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2 papers

Recent·Most cited

Profibrotic priming of airway cell types and drug responses in early-stage idiopathic pulmonary fibrosis

Robert Lorenz Chua, Carmen Veith, Marc Andre Schneider, Katharina Jechow, Elizabeth Chang Xu, Michael Kreuter, Agnes W. Boots, Roland Eils, Nicolas Carlos Kahn, Christian Conrad

This study uses early-stage IPF patient-derived cells to identify proinflammatory and fibrotic states and assess drug responses in airway cells.

bioRxiv · Mar 9, 2022 · PreprintMolecular Biology

SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches

Soeren Lukassen, Robert Lorenz Chua, Timo B. Trefzer, Nicolas Carlos Kahn, Marc Andre Schneider, Thomas Muley, Hauke Winter, Michael A. Meister, Carmen Veith, Agnes W. Boots, Bianca P. Hennig, Michael Kreuter, Christian Conrad, Roland Eils

Single-cell profiling of lung and bronchial cells places ACE2 mainly in a transient secretory cell state of cultured bronchial epithelium, between goblet and ciliated cells, co-expressing TMPRSS2.

The EMBO Journal · Apr 14, 2020Peer-reviewedGenomics✦ In-depth digest