Robert Lorenz Chua

This study uses single-cell transcriptomics to show that SARS-CoV-2 variants reshape pediatric upper-airway immunity differently from adults.

The paper constructs a single-cell multiomics atlas of the human pancreas across development, health, and T2D, identifying plastic cell states and lineage trajectories.

This study uses long-read single-cell RNA sequencing to identify cell-type specific alternative splicing changes in COVID-19 patients compared to healthy controls.

This study identifies ELF5 as a risk gene for severe COVID-19 using genetic and single-cell expression data, showing its specific expression in respiratory epithelial cells.

This study uses early-stage IPF patient-derived cells to identify proinflammatory and fibrotic states and assess drug responses in airway cells.

The paper investigates SARS-CoV-2 entry into the CNS via the olfactory mucosa in COVID-19 patients and demonstrates neurotropism and cerebral thromboembolism.

Single-cell profiling of lung and bronchial cells places ACE2 mainly in a transient secretory cell state of cultured bronchial epithelium, between goblet and ciliated cells, co-expressing TMPRSS2.