ImmunologyNature CommunicationsPeer-reviewed
Availability of an inflammatory macrophage niche drives phenotypic and functional alterations in Kupffer cells
Han-Ying Huang, Yan-Zhou Chen, Chuang Zhao…·Lin Hai Tian
The paper shows that blocking monocytes alone is insufficient to reduce LMAMs, as KCs can replenish them through proliferation or infiltration, and their reprogramming contributes to immunosuppression.
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