Huai‐Qiang Ju

This paper shows YTHDF2 upregulation and nuclear relocation enhance CD8 T cell polyfunctionality and tumor immunity by regulating gene transcription and mitochondrial fitness.

The paper shows that blocking monocytes alone is insufficient to reduce LMAMs, as KCs can replenish them through proliferation or infiltration, and their reprogramming contributes to immunosuppression.

dSCOPE predicts sequence segments critical for liquid-liquid phase separation (SCOPEs) using a random forest model trained on curated experimental data, showing enrichment in post-translational modifications and cancer mutations.