Andrea Schmitt

This study identifies shared genetic architecture between schizophrenia and substance use disorders using GWAS and genomic methods, finding significant genetic correlations and bidirectional causal relationships.

The paper develops pathway-specific polygenic scores to predict lithium treatment response in bipolar disorder and finds associations with specific biological pathways.

The paper evaluates how different functional connectivity metrics affect neuroimaging results and identifies metrics best suited for detecting age-related neural decline.

The paper identifies amacrine cells as enriched in schizophrenia genetic risk and links this to synaptic biology, while finding retinal immune cells associated with multiple sclerosis.

This study identifies alternative polyadenylation (APA) as a molecular mechanism linking polygenic risk for schizophrenia to synaptic impairments through functional analysis in induced neurons.

The paper investigates how psychiatric disease and aging affect FKBP5 expression in the human brain, identifying supragranular neurons as key targets.