Dóra Koller

This study identifies shared genetic architecture between schizophrenia and substance use disorders using GWAS and genomic methods, finding significant genetic correlations and bidirectional causal relationships.

This study identifies 80 genome-wide significant associations for endometriosis and adenomyosis in 1.4 million women, uncovering novel loci and pathways involved in disease mechanisms.

This study identifies shared genetic loci and genes between PTSD and cardiovascular conditions using GWAS across multiple data sources and finds overlapping biological pathways and drug targets.

This study investigates sex differences in the genetic pleiotropy between hearing difficulty and brain imaging-derived phenotypes using large-scale GWAS data and multiple analytical methods.

This study identifies 51 anxiety-associated genetic loci from a multi-ancestry GWAS of 1.2 million participants and highlights genetic correlations with other mental and physical health conditions.

This study investigates genetic correlations between COVID-19 outcomes and anxiety disorders/symptoms using large-scale genomic datasets, finding bidirectional genetic causality and shared loci related to lung function and brain morphology.

This study identifies 46 genetically correlated traits with ALS using GWAS data and performs causal inference, finding bidirectional genetic effects on several traits.

The paper tests if self-domestication and neural crest loci contribute to neurodevelopmental disorder heritability, finding significant enrichments that disappear when other genomic annotations are included.

This paper conducts a multi-ancestry GWAS of major depression, identifying 190 loci and 354 genes, with findings showing increased fine-mapping power and bidirectional BMI relationship in European ancestry samples.

This study identifies 54 risk loci for hearing loss in adults across multiple cohorts, revealing sex differences, ancestry-specific polygenic risks, and interactions with environmental factors like noise and smoking.

This study analyzes ancestry diversity changes in the Million Veteran Program over time and shows that refined ancestry modeling reduces population stratification in GWAS of height.

This paper integrates genetic transcriptomics and electronic health records to show increased hepatic Transthyretin expression is linked to specific surgical procedures and health outcomes like osteoarthritis and carpal tunnel syndrome.

The paper functionally characterizes the ACE2 gene network to identify potential mechanisms of COVID-19 susceptibility and drug-gene interactions.

The paper investigates how evolutionary processes, including Denisovan and Neanderthal introgression, affect the genetics of complex traits in East Asians using genome-wide association data.

This paper identifies associations between NAT2 haplotype variation and simvastatin use, showing NAT2*1 is linked to better response to simvastatin therapy.