Author

Nick J. Lane

University College LondonORCID 0000-0002-5433-3973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andrew PomiankowskiiD· 2 shared Anna M. G. Novák VanclováiD· 1 shared Ekin DaplaniD· 1 shared Enrique RodrígueziD· 1 shared Joel B. DacksiD· 1 shared Lisa MatsuoiD· 1 shared Luca TuriniD· 1 shared M. Florencia CamusiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

Andrew PomiankowskiORCID

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4 papers

Recent·Most cited

Mitonuclear interactions shape male cuticular hydrocarbon profiles with consequences on mating success

Tom M. Allison, Stuart A. Harrison, Nick J. Lane, M. Florencia Camus

The paper shows mitonuclear compatibility affects cuticular hydrocarbon profiles in Drosophila, influencing mating success.

bioRxiv · Apr 1, 2026 · PreprintEvolutionary Biology

Eukaryotic recombinases duplicated after divergence from known asgardarchaeal RadA: implications for the evolution of sex during eukaryogenesis

Lisa Matsuo, Anna M. G. Novák Vanclová, Andrew Pomiankowski, Nick J. Lane, Joel B. Dacks

The paper uses comparative genomics and phylogenetic analysis to show eukaryotic Rad51 and DMC1 proteins diverge from asgardarchaeal RadA, supporting a model of eukaryogenesis involving mitochondrial acquisition and sex evolution.

Genome Biology and Evolution · Nov 28, 2025Peer-reviewedEvolutionary Biology

First growth, then information: the path to genetic heredity in protocells

Raquel Nunes Palmeira, Marco Colnaghi, Andrew Pomiankowski, Nick J. Lane

This paper develops a mathematical model showing that growth-supporting functions evolved before informational processes in protocells, establishing a fundamental constraint on the origin of genetic heredity.

bioRxiv · Nov 17, 2025 · PreprintEvolutionary Biology

A chance insight into phosgene toxicity

Ekin Daplan, Enrique Rodríguez, Nick J. Lane, Luca Turin

The paper uses ESR spectroscopy on fruit flies to show phosgene causes Mn(II) hyperfine signals linked to mitochondrial dysfunction and toxicity.

bioRxiv · Apr 23, 2024 · PreprintPharmacology & Toxicology