Author

Josh J. Sekela

University of North Carolina at Chapel HillORCID 0000-0002-5439-491XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:mouse· 2

Frequent Co-Authors

Aadra Prashant BhattiD· 2 shared Jianan ZhangiD· 2 shared Matthew R. RedinboiD· 2 shared Rani S. SellersiD· 2 shared Ajay GulatiiD· 1 shared Jun J. YangiD· 1 shared Lauren HutchinsoniD· 1 shared Meredith J. ZelleriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Aadra Prashant BhattORCID

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2 papers

Recent·Most cited

MicrobiologyGut Microbes ReportsPeer-reviewedDec 7, 2025

Commercially Purchased and In-House Bred C57BL/6 Mice with Different Gut Microbiota Exhibit Distinct Indomethacin-Induced Toxicities

Jianan Zhang, Rose Viguna Thomas Becket, Josh J. Sekela…·Aadra Prashant Bhatt

This study shows that C57BL/6 mice from different vendors have distinct gut microbiomes, leading to different levels of indomethacin-induced intestinal toxicity.

DOI 10.1080/29933935.2025.2585683

mousemetagenomics

𝕏 PostBluesky

BiochemistryScientific ReportsPeer-reviewedOct 15, 2025

Sex-Dependent Responses in Mice to Indomethacin-Induced Injury and Gut Microbiome-Targeted Alleviation

Jianan Zhang, Josh J. Sekela, Lauren Hutchinson…·Matthew R. Redinbo

This study examines sex-dependent responses to indomethacin-induced injury in mice and shows that a GUS inhibitor alleviates sex-specific toxicities.

2 citations

mousemetagenomics

𝕏 PostBluesky