Author

Aadra Prashant Bhatt

University of North Carolina at Chapel HillORCID 0000-0002-0134-6543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Jianan ZhangiD· 2 shared Josh J. SekelaiD· 2 shared Matthew R. RedinboiD· 2 shared Rani S. SellersiD· 2 shared Ajay GulatiiD· 1 shared Anna C. SalvadoriD· 1 shared Ayesh Awad· 1 shared Benjamin D. McMichaeliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersMicrobiology

Jianan ZhangORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Fatty Acid Oxidation Suppression Reprograms Fibroblasts in Fibrostenotic Crohns Disease

Jihad Jihad Aljabban, Ayesh Awad, Benjamin D. McMichael, Valerie Gartner, Viguna Thomas, Bingfang Huan, David Weaver, Grace Lian, Caroline Beasley, Gwen W. Lau, Sophie Silverstein, Muneera Rehana Kapadia, Anna C. Salvador, Florian Rieder, Jessica E. Thaxton, , Shehzad Z. Sheikh

The paper identifies impaired fatty acid oxidation in fibroblasts from fibrostenotic Crohn's disease patients and links it to intestinal fibrosis.

bioRxiv · May 10, 2026 · PreprintGenomics

Commercially Purchased and In-House Bred C57BL/6 Mice with Different Gut Microbiota Exhibit Distinct Indomethacin-Induced Toxicities

Jianan Zhang, Rose Viguna Thomas Becket, Josh J. Sekela, Meredith J. Zeller, Rani S. Sellers, Matthew R. Redinbo, Ajay Gulati, Aadra Prashant Bhatt

This study shows that C57BL/6 mice from different vendors have distinct gut microbiomes, leading to different levels of indomethacin-induced intestinal toxicity.

Gut Microbes Reports · Dec 7, 2025Peer-reviewedMicrobiology

Sex-Dependent Responses in Mice to Indomethacin-Induced Injury and Gut Microbiome-Targeted Alleviation

Jianan Zhang, Josh J. Sekela, Lauren Hutchinson, Jun J. Yang, Rani S. Sellers, Aadra Prashant Bhatt, Matthew R. Redinbo

This study examines sex-dependent responses to indomethacin-induced injury in mice and shows that a GUS inhibitor alleviates sex-specific toxicities.

Scientific Reports · Oct 15, 2025Peer-reviewedBiochemistry