Jianan Zhang

This study shows that GSDMA undergoes S-acylation, which promotes pyroptosis by enhancing membrane anchoring and oligomerization, distinct from GSDMD's palmitoylation mechanism.

This study shows that C57BL/6 mice from different vendors have distinct gut microbiomes, leading to different levels of indomethacin-induced intestinal toxicity.

The paper identifies lipid metabolic pathway inhibitors that modulate STING signaling and IFN induction in mouse and human cells.

This study examines sex-dependent responses to indomethacin-induced injury in mice and shows that a GUS inhibitor alleviates sex-specific toxicities.