Author

Shan Wu

State Key Laboratory of Biocatalysis and Enzyme EngineeringORCID 0000-0002-5449-7580Unclaimed ORCID profile · follow to get notified of new preprints

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Shan Wu1 paper · State Key Laboratory of Biocatalysis and Enzyme Engineering

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anna QiaoiD· 1 shared Chulun Wang· 1 shared Jiening WangiD· 1 shared Sheng YeiD· 1 shared Tao Zhou· 1 shared Yi Zhang· 1 shared Zhen Han· 1 shared Zishao Ouyang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Anna QiaoORCID

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1 paper

Recent·Most cited

Structural Basis of Ligand-Specific Orthosteric-Allosteric Coupling and Sensory Tuning in the Human Bitter Taste Receptor TAS2R14

Tao Zhou, Jiening Wang, Chulun Wang, Zhen Han, Yi Zhang, Zishao Ouyang, Sheng Ye, Shan Wu, Anna Qiao

The paper reports cryo-EM structures of TAS2R14-Gi1 complexes bound to different ligands, revealing TM6 dynamics that govern agonist efficacy and allosteric-orthosteric coupling.

bioRxiv · May 17, 2026 · PreprintMolecular Biology