Author

Jiening Wang

State Key Laboratory of Biocatalysis and Enzyme EngineeringORCID 0000-0002-1728-0358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Anna QiaoiD· 1 shared Chengji YangiD· 1 shared Chulun Wang· 1 shared Gaojie SongiD· 1 shared Guan WangiD· 1 shared Guobao LiiD· 1 shared Heng RuiD· 1 shared Kaihua ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMolecular Biology

Anna QiaoORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 17, 2026

Structural Basis of Ligand-Specific Orthosteric-Allosteric Coupling and Sensory Tuning in the Human Bitter Taste Receptor TAS2R14

Tao Zhou, Jiening Wang, Chulun Wang…·Anna Qiao

The paper reports cryo-EM structures of TAS2R14-Gi1 complexes bound to different ligands, revealing TM6 dynamics that govern agonist efficacy and allosteric-orthosteric coupling.

DOI 10.64898/2026.05.14.725165

humanprotein structure

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MicrobiologybioRxivPreprintJul 21, 2025

Structural insights into Measles virus RNA synthesis: C protein-mediated regulation of replication-transcription switch and allosteric inhibition by ERDRP-0519

Tianjiao Du, Jiening Wang, Chengji Yang…·Heng Ru

This study reveals how MeV C protein regulates RNA synthesis by stabilizing the RdRP complex and shows how ERDRP-0519 inhibits viral replication through an allosteric mechanism.

DOI 10.1101/2025.07.21.666041

virusstructural biology

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BiochemistrybioRxivPreprintJun 17, 2024

Oligopeptide (FK)4 facilitates the determination of the absolute stereochemistry of chiral organic compounds via NMR Spectroscopy

Mingjun Zhu, Yun Peng, Kaihua Zhang…·Maili Liu

This study demonstrates how the oligopeptide (FK)4 enables the determination of absolute stereochemistry of chiral compounds using NMR spectroscopy by combining alignment medium and chiral differentiating properties.

DOI 10.1101/2024.06.17.599446

experimental assay

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