Author

Tommaso Volpi

Yale UniversityORCID 0000-0002-5451-6710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:imaging· 5 Organism:human· 4 Approach:statistical model· 4 Research Focus:benchmarking· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Alessandra BertoldoiD· 3 shared Andrei G. VlassenkoiD· 3 shared Manu S. GoyaliD· 3 shared Claudia TarriconeiD· 2 shared Massimiliano Facca· 2 shared Maurizio CorbettaiD· 2 shared Akshita ChhabraiD· 1 shared Alexander HammersiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Alessandra BertoldoORCID

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5 papers

Recent·Most cited

Unveiling functional-metabolic synergy in the healthy brain: multivariate integration of dynamic FDG-PET and resting-state fMRI

Claudia Tarricone, Giulia Vallini, Giorgia Baron, Massimiliano Facca, Erica Silvestri, Tommaso Volpi, Andrei G. Vlassenko, Manu S. Goyal, Alessandra Bertoldo

This paper uses multivariate PLSC to analyze functional-metabolic coupling in the brain, finding strong links between fMRI-derived functional connectivity and glucose metabolism parameters.

Human Brain Mapping · Sep 30, 2026Peer-reviewedNeuroscience

Glucose Metabolism echoes Long-Range Temporal Correlations in the Human Brain

Massimiliano Facca, Anna Ridolfo, Miriam Celli, Claudia Tarricone, Ilaria Mazzonetto, Tommaso Volpi, Andrei G. Vlassenko, Manu S. Goyal, Maurizio Corbetta, Alessandra Bertoldo

This study links long-range temporal correlations in brain activity to glucose metabolism and biosynthetic processes, showing higher correlations correlate with greater metabolic costs.

Imaging Neuroscience · Jan 1, 2026Peer-reviewedNeuroscience

Condensates of synaptic vesicles and synapsin are molecular beacons for actin sequestering and polymerization

Akshita Chhabra, Christian Hoffmann, Gerard Aguilar Pérez, Александр Коробейников, Jakob Rentsch, Nadja Hümpfer, Linda Kokwaro, Luka Gnidovec, Arsen Petrović, Jaqulin N. Wallace, Johannes Vincent Tromm, Cristina Román‐Vendrell, Emma Johnson, Branislava Ranković, Eleonora Perego, , Dragomir Milovanović

The paper investigates how synapsin-SV condensates organize presynaptic actin through LLPS, revealing their role in SV clustering and actin polymerization in lamprey and mammalian synapses.

The EMBO Journal · Aug 14, 2025Peer-reviewedCell Biology

The brain's "dark energy" puzzle upgraded: FDG uptake, delivery and phosphorylation, and their coupling with resting-state brain activity

Tommaso Volpi, John J. Lee, Andrei G. Vlassenko, Manu S. Goyal, Maurizio Corbetta, Alessandra Bertoldo

The paper predicts [18F]FDG PET parameters using rs-fMRI and 15O PET data, showing rs-fMRI and CMRO2 explain 45% of Ki variance.

Journal of Cerebral Blood Flow & Metabolism · May 15, 2025Peer-reviewedNeuroscience

Connecting the Dots: Approaching a Standardized Nomenclature for Molecular Connectivity Combining Data and Literature

Murray Bruce Reed, Luca Cocchi, Gitte M. Knudsen, Christin Y.M. Sander, Gregor Gryglewski, J Chen, Tommaso Volpi, Patrick M. Fisher, Nikkita Khattar, L. Silberbauer, Matej Murgaš, Godber Mathis Godbersen, Lukas Nics, Martin Walter, Marcus Hacker, , Andreas Hahn

The paper introduces a standardized nomenclature for PET-based molecular connectivity and covariance to improve reproducibility and interpretation across imaging modalities and radiotracers.

bioRxiv · May 10, 2024 · PreprintNeuroscience