Eleonora Perego

BrightEyes-FFS provides an open-source platform for analyzing fluorescence fluctuation spectroscopy data with small detector arrays, offering tools for data processing, correlation analysis, and model fitting.

This study visualizes and characterizes the diffusivity of NEAT1-1 in live cells, revealing its presence in a distinct diffusive state within the nucleoplasm.

The paper investigates how synapsin-SV condensates organize presynaptic actin through LLPS, revealing their role in SV clustering and actin polymerization in lamprey and mammalian synapses.

This study investigates how RNA affects alpha-synuclein phase separation, showing RNA induces morphological changes and promotes liquid-to-solid transition.

This study examines how ALS-associated FUS mutations alter the RNA and protein composition of Stress Granules in neural cells, revealing molecular changes linked to neurodegeneration.

The paper shows that reducing m6A content via METTL3 knock-down decreases FUS-associated ALS granules in cell models and patient-derived fibroblasts.