Peter McColgan

This study compares motor cortex microstructure in humans and chimpanzees using qMRI, finding conserved high myelin and iron content in the hand-knob but enhanced rightward lateralization in humans.

The paper shows that white matter macrostructure loss and elevated plasma neurofilament light chain levels are associated with poor outcomes in Parkinson's disease.

The paper links quantitative MRI parameters to cell type-specific gene expression in human neocortex, showing associations with GABA- and glutamatergic neurons and other cell types.

The paper examines dynamic brain state transitions in Parkinson's disease patients with visual hallucinations, finding altered temporal dynamics and links to neurotransmitter systems.

The paper investigates WM loss in premanifest HD, finding early reductions in specific tracts 11 years before onset and correlations with motor scores.

The paper shows that visual dysfunction in Parkinson's disease is linked to cognitive decline and white matter damage over time.

The paper evaluates graph thresholding and streamline filtering methods for structural connectome construction in Huntington's disease, finding that SIFT2 filtering improves group difference detection and clinical correlations.

This study compares functional connectome construction strategies in neurodegeneration, finding that principal component-based correction and weighted unthresholded networks best discriminate HD gene carriers from controls.