Systems BiologybioRxivPreprint
PDE-constrained optimization for estimating population dynamics over cell cycle from static single cell measurements
Karsten Kuritz, Alain R. Bonny, João Pedro Fonseca, Frank Allgöwer
The paper introduces a PDE-constrained optimization framework to estimate cell cycle dynamics from static single-cell data, showing it can identify M-phase arrest in treated K562 cells.