João Pedro Fonseca

The paper uses ribosomal DNA markers to study the phylogeny of Ulex L., finding evidence of allopolyploidy in several species and suggesting it played a major role in the genus's radiation.

The paper introduces TuNR, a synthetic circuit that independently controls mean and variability of gene expression in human cells, enabling study of cell-to-cell heterogeneity.

The paper identifies genes with biphasic expression in response to increasing cAMP levels and shows PKA and ERK1/2 exhibit opposite biphasic responses, revealing complex signaling integration.

The paper introduces a PDE-constrained optimization framework to estimate cell cycle dynamics from static single-cell data, showing it can identify M-phase arrest in treated K562 cells.

The paper introduces MTK, a toolkit for rapid modular DNA circuit assembly in mammalian cells, demonstrating its use in constructing an Ebola virus replication complex circuit.