Author

Atagun U. Isiktas

Yale UniversityORCID 0000-0002-5459-6810Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Aziz Eshov· 2 shared Junjie U. GuoiD· 2 shared Jeffrey ZhouiD· 1 shared Suzhou YangiD· 1 shared Yu SuniD· 1 shared

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2020-2022 · peak 1/yr

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5 top collaborators · 8 mutual co-author links

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2 shared papersMolecular Biology

Aziz Eshov

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 11, 2022

Systematic generation and imaging of tandem repeats reveal multivalent base-pairing as a major determinant of RNA aggregation

Atagun U. Isiktas, Aziz Eshov, Suzhou Yang, Junjie U. Guo

The paper systematically generates tandem repeats to identify sequence features driving RNA aggregation, finding multivalent base-pairing as a key mechanism.

DOI 10.1101/2022.04.11.487960

humanDNA methylation

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Molecular BiologyNature CommunicationsPeer-reviewedJul 3, 2020

C9orf72 dipeptide repeats inhibit UPF1-mediated RNA decay independent of stress granule formation

Yu Sun, Aziz Eshov, Jeffrey Zhou…·Junjie U. Guo

This study shows that C9orf72 dipeptide repeats inhibit UPF1-mediated RNA decay without requiring stress granule formation, contributing to RNA accumulation in c9ALS/FTD.

57 citationstop 4%

humanexperimental assay

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