Incorporation of macrophage immune stresses into an assay for drug tolerance in intracellular Mycobacterium tuberculosis
Greana Kirubakar, Luana Johnston, Bom Nae Rin Lee, David G. Russell, Nelson V. Simwela
This paper develops a 96-well plate assay to identify anti-TB drugs effective against drug-tolerant Mtb in macrophages, showing host immune stresses can induce tolerance or synergize with certain drugs.
Antimicrobial Agents and Chemotherapy · Sep 11, 2025Peer-reviewedMicrobiology