Svetlana Dzitoyeva

The roles of TGFβ and serotonin signaling in regulating proliferation of oocyte precursors and germline aging

This study identifies TGFβ and serotonin signaling pathways that regulate oocyte precursor proliferation and germline aging in C. elegans.

Serotonergic signaling plays a deeply conserved role in improving oocyte quality

This study shows serotonin signaling improves oocyte quality in C. elegans and D. melanogaster, suggesting a conserved role in germline health and potential therapeutic applications.

Serotonin coordinates reproductive functions in Caenorhabditis elegans

This study identifies a serotonin-mediated neuronal circuit in C. elegans that coordinates reproductive functions, including germline proliferation and oocyte quality.

Egg activation triggers clearance of maternally deposited RNA binding proteins

The paper shows that egg activation triggers the degradation of maternally deposited RNA binding proteins via the ubiquitin-proteasome system, mediated by Kondo and CTLH ligase.