Chloe L. Barrington

This study demonstrates the use of updated nanopore sequencing to characterize 43 RNA modifications in tRNAs, including mitochondrial and viral tRNAs, and provides best practices for future research.

The paper shows that nonoptimal codon usage represses translation initiation, reducing protein levels independently of transcript abundance or stability.

The paper shows that egg activation triggers the degradation of maternally deposited RNA binding proteins via the ubiquitin-proteasome system, mediated by Kondo and CTLH ligase.