One night of sleep deprivation reduces spatially patterned human brain clearance: implications for simulated tau propagation
Georgia S. Brennan, Travis Thompson, Hadrien Oliveri, Vegard Vinje, Geir André Ringstad, Per Kristian Eide, Alain Goriely, Marie Elisabeth Rognes
This study shows that sleep deprivation reduces brain clearance rates but preserves their spatial pattern, affecting tau propagation differently in a computational model.
bioRxiv · Jun 3, 2025 · PreprintNeuroscience