Author

Guoqiang Zhu

Yangzhou UniversityORCID 0000-0002-5491-0670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aaron P. WhiteiD· 2 shared Xin Cao· 2 shared Yejun WangiD· 2 shared Yueming HuiD· 2 shared Akosiererem S. SokariboiD· 1 shared Cuihua Cao· 1 shared Gaofeng Hao· 1 shared Haoyi ZhangiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Aaron P. WhiteORCID

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3 papers

Recent·Most cited

Genome-wide investigation of outer membrane protein families under mosaic evolution in Escherichia coli

Xin Cao, Cuihua Cao, Zefan Chen, Jialin Li, Zikun Yao, Yidong Zheng, Jinjin Wu, Zeling Li, Yueming Hu, Gaofeng Hao, Guoqiang Zhu, Wolfgang L. Köster, Aaron P. White, Yejun Wang

The paper identifies 21 OMP families in E. coli showing mosaic evolution, including 16 new families, and links their variable regions to immunogenicity and antigenicity.

Applied and Environmental Microbiology · May 30, 2025Peer-reviewedMicrobiology

Next-Generation saRNA Platforms: Systematic Screening and Engineering Enhances Superior Protein Expression and Organ-Specific Targeting for RNA Therapeutics

Zhen Feng Sun, Yuxiao Liu, Haoyi Zhang, Ting Ge, Yuting Pan, Yang Liu, Miaomiao Wu, Tao Shan, Guoqiang Zhu, Qi Wu, Kangming Chen

This paper optimizes saRNA platforms for enhanced protein expression and organ-specific targeting, identifying three alphavirus-derived constructs with improved performance in vivo.

bioRxiv · Mar 30, 2025 · PreprintMolecular Biology

Evolution of Salmonella Chromosomes and Its Influence on Gene Expression and Chromosomal Conformation

Yueming Hu, Zewei Chen, Akosiererem S. Sokaribo, Ziyi Zhao, Xin Cao, Junya Zhang, Shuhong Liu, Runhong Chen, Yuping Deng, Hongxia Bao, Xinjie Hui, Ming-an Sun, Guoqiang Zhu, Shulin Liu, Aaron P. White, Yejun Wang

This study reconstructs ancient Salmonella chromosomes and shows genetic rearrangements affect gene expression and chromosomal conformation across lineages.

bioRxiv · Dec 10, 2024 · PreprintMicrobiology