Molecular BiologybioRxivPreprint
Next-Generation saRNA Platforms: Systematic Screening and Engineering Enhances Superior Protein Expression and Organ-Specific Targeting for RNA Therapeutics
Zhen Feng Sun, Yuxiao Liu, Haoyi Zhang…·Kangming Chen
This paper optimizes saRNA platforms for enhanced protein expression and organ-specific targeting, identifying three alphavirus-derived constructs with improved performance in vivo.
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