Author

Miina Ojansivu

Karolinska University HospitalORCID 0000-0002-5493-3530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Antonin MarquantiD· 2 shared E. FilipiakiD· 2 shared Julia RädleriD· 2 shared Małgorzata HoncharenkoiD· 2 shared Rula ZainiD· 2 shared Samantha RoudiiD· 2 shared Samir EL AndaloussiiD· 2 shared Tomasz CzapikiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Antonin MarquantORCID

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Author profile →

2 papers

Recent·Most cited

Enhancing the efficacy of siRNA Antibody Oligonucleotide Conjugates (AOCs) through chemical design

Oliver G. Hayes, Julia Rädler, E. Filipiak, Tomasz Czapik, Samantha Roudi, Miina Ojansivu, Hema Saranya Ilamathi, Antonin Marquant, Yanjie Huang, Oscar P. B. Wiklander, Rula Zain, Małgorzata Honcharenko, Samir EL Andaloussi

This study shows that chemical modifications to siRNA and linkers in AOCs can improve potency and tissue targeting while allowing higher payload loading.

bioRxiv · Sep 23, 2026 · PreprintBiochemistry

Click Chemistry-Based Strategy for Modular Ligand Attachment to siRNAs: Toward Extrahepatic RNAi

Julia Rädler, E. Filipiak, Antonin Marquant, Miina Ojansivu, Tomasz Czapik, Alyssa C. Hill, Nina Ahlskog, Samantha Roudi, Cristiana Barradas, Yanjie Huang, Osama Saher, Matthew Wood, Rula Zain, Małgorzata Honcharenko, Samir EL Andaloussi

This study develops a click chemistry-based strategy for siRNA conjugation to enhance extrahepatic RNAi, finding that bis-fatty-acid conjugates improve activity in heart and muscle while showing modality-specific limitations.

bioRxiv · May 22, 2026 · PreprintMolecular Biology