From Peaks to Power: Systematic Evaluation of Chromatographic Sampling Reveals Determinants of Quantification and Biological Discovery in DIA Proteomics
Lee S. Cantrell, Seth Just, Alexey Stukalov…·Serafim Batzoglou
This study evaluates how chromatographic sampling affects quantification and biological discovery in DIA proteomics, finding that statistical power and LOQ are more critical than identifications.