Author

James I. McDonald

Western UniversityORCID 0000-0002-5497-0083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

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Frederick A. DickiD· 1 shared Pirunthan Perampalam· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperSystems Biology

Frederick A. DickORCID

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1 paper

Recent·Most cited

Systems BiologyPLoS ONEPeer-reviewedDec 18, 2024

GO-CRISPR: a highly controlled workflow to discover gene essentiality in loss-of-function screens

Pirunthan Perampalam, James I. McDonald, Frederick A. Dick

GO-CRISPR improves loss-of-function CRISPR screens by integrating guide-only controls and TRACS software, identifying novel pathways in tumor dormancy.

6 citations

humanCRISPR screen

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