The paper investigates how centromeric satellite array size asymmetry affects meiotic function in mice, finding that small arrays paired with larger ones lead to chromatin and spindle defects and increased aneuploidy.

bioRxiv · May 18, 2026 · PreprintCell Biology

Replication Protein A1 is essential for DNA damage repair during mammalian oogenesis

Xiaosu Miao, Rui Guo, Andrea Williams, Kaylei Wong, Vienna Rivard, Catherine A. A. Lee, Jun Ma, P. Jeremy Wang, Wei Cui

This study shows that RPA1 is critical for DNA damage repair in oocytes, leading to infertility when disrupted.

Biology of Reproduction · Feb 25, 2026Peer-reviewedDevelopmental Biology

Centromere Innovations Within a Mouse Species

Craig W. Gambogi, Nootan Pandey, Jennine M. Dawicki-McKenna, Uma P. Arora, Mikhail A. Liskovykh, Jun Ma, Piero Lamelza, Vladimir Larionov, Michael A. Lampson, Glennis A. Logsdon, Beth L. Dumont, Ben E. Black

The paper describes a novel centromere structure in the mouse species Mus pahari, characterized by a divergent repeat and unique CENP-B recruitment, enabling high-fidelity segregation during cell division.

Science Advances · Nov 15, 2023Peer-reviewedGenomics

Prognostic Roles of LncRNA XIST and Its Potential Mechanisms in Human Cancers: A Pan-Cancer Analysis

Wei Han, Chun-tao Shi, Jun Ma, Qixiang Shao, Xiao‐Jiao Gao, Haonan Wang

This paper analyzes XIST expression and its prognostic roles across multiple cancers using public databases, finding it associated with prognosis, miRNAs, immune infiltration, and mutations.

bioRxiv · Jun 16, 2021 · PreprintBioinformatics