Author

Catherine A. A. Lee

Sanford Burnham Prebys Medical Discovery InstituteORCID 0000-0001-8525-9342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea Williams· 1 shared Brian L. GudenasiD· 1 shared Charles KaraniD· 1 shared Grace Furnari· 1 shared Jacob Torrejon-DiaziD· 1 shared Jun MaiD· 1 shared Kaylei Wong· 1 shared Kendall R. ChambersiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Andrea Williams

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2 papers

Recent·Most cited

Replication Protein A1 is essential for DNA damage repair during mammalian oogenesis

Xiaosu Miao, Rui Guo, Andrea Williams, Kaylei Wong, Vienna Rivard, Catherine A. A. Lee, Jun Ma, P. Jeremy Wang, Wei Cui

This study shows that RPA1 is critical for DNA damage repair in oocytes, leading to infertility when disrupted.

Biology of Reproduction · Feb 25, 2026Peer-reviewedDevelopmental Biology

Ras-Responsive Element Binding Protein 1 regulates survival of Group 3 medulloblastoma

Meher Beigi Masihi, Kendall R. Chambers, Richard A. Friedman, Sergey Pampou, Brian L. Gudenas, Jacob Torrejon-Diaz, Catherine A. A. Lee, Grace Furnari, Lianne Q. Chau, Sajina GC, Yingxi Lin, Owen S. Chapman, Patryk Skowron, Livia Garzia, Michael D. Taylor, , Robert J. Wechsler‐Reya

This study identifies RREB1 as a key driver of Group 3 medulloblastoma, showing its role in tumor growth and survival through the c-MET signaling pathway.

bioRxiv · Jul 16, 2025 · PreprintCancer Biology