NeurosciencebioRxivPreprint
Parvalbumin Interneuron Activity Underlies Vulnerability to Post-Traumatic Stress Disorder in Autism
Alice Shaam Al Abed, Tiarne Vickie Allen, Noorya Yasmin Ahmed…·Nathalie Dehorter
This study shows that stress-induced PTSD-like memory worsens ASD traits in mice through hyperactivation of the prefrontal cortex and parvalbumin interneuron dysfunction, and suggests recontextualization as a potential treatment.
DOI 10.1101/2021.01.18.427217