Alice Shaam Al Abed

Reduced dorsal CA1 Activity Limits Retention of the Temporal Component of Declarative Memory in the Cntnap2 Knockout Mouse Model of Autism

This study shows that reduced dorsal CA1 activity in Cntnap2 knockout mice impairs temporal memory retention and flexible spatial memory, linking hippocampal dysfunction to cognitive inflexibility in autism.

The correct temporal connectivity of the DG CA3 circuits involved in declarative memory processes depends on Vangl2-dependent planar cell polarity signaling

This study identifies Vangl2 as essential for the morphogenesis and function of MfB/TE synapses in the hippocampus and shows its role in declarative memory processes.

Glutamine Transport via Neurotransmitter Transporter 4 (NTT4, SLC6A17) Maintains Presynaptic Glutamate Supply at Excitatory Synapses in the Central Nervous System

This study identifies NTT4/SLC6A17 as a presynaptic glutamine transporter essential for glutamate supply and neurotransmission, with behavioral implications.

Loss of the Er81 Transcription Factor in Cholinergic Cells Alters Striatal Activity and Habit Formation

This study shows that loss of the Er81 transcription factor in cholinergic interneurons alters their electrophysiological properties and impairs habit formation in adult mice.

Parvalbumin Interneuron Activity Underlies Vulnerability to Post-Traumatic Stress Disorder in Autism

This study shows that stress-induced PTSD-like memory worsens ASD traits in mice through hyperactivation of the prefrontal cortex and parvalbumin interneuron dysfunction, and suggests recontextualization as a potential treatment.