Author

Chan Lee

Harvard UniversityORCID 0000-0002-5512-8146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:metagenomics· 1

Frequent Co-Authors

J. Wade HarperiD· 2 shared João A. PauloiD· 2 shared Anna BieberiD· 1 shared Annie JeniD· 1 shared Benton J. AndersoniD· 1 shared Brenda Arlene SchulmaniD· 1 shared Cristina CapitanioiD· 1 shared Felix KrausiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

J. Wade HarperORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 29, 2026

✦ In-depth digest

Structural Mechanisms of DNAJC13 Dimeric Assembly and InsP6 binding in Recycling Endosome Regulation

Tao Fu, Chan Lee, Frances V Hundley…·J. Wade Harper

Cryo-EM at 2.4 Å shows DNAJC13 as an antiparallel arch-shaped homodimer with a buried InsP6 pocket; dimerization controls WASH recruitment, tubule fission, and melanin production.

1 citation

humanprotein structure

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Cell BiologyScience AdvancesPeer-reviewedJan 22, 2025

Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST

Felix Kraus, Yuchen He, Sharan Swarup…·J. Wade Harper

This study uses nMOST to profile proteo-lipidomics in lysosomal storage disease mutants, revealing autophagy defects and mitochondrial dysfunction.

13 citationstop 1%

humanproteomics

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