Author

Mark G. Lazarev

Johns Hopkins UniversityORCID 0000-0002-5517-3588Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Joanna MeliaiD· 2 shared Alyssa M. ParianiD· 1 shared Caitlin M. TressleriD· 1 shared Florin M. SelaruiD· 1 shared Franck HousseauiD· 1 shared Jessica LiniD· 1 shared John Kang· 1 shared Kellie Nicole SmithiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Joanna MeliaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 13, 2025

Longitudinal T cell repertoire analysis reveals dynamic clonal T cell populations in Ulcerative Colitis

Kristi Briggs, Jessica Lin, Lara Chaaban…·Joanna Melia

This study analyzes the TCR repertoire in UC patients over time, finding most do not share persistent clones, while a subset has persistent clones linked to more active disease.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 28, 2024

Aberrant N-glycosylation is a therapeutic target in carriers of a common and highly pleiotropic mutation in the manganese transporter ZIP8

Vartika Tomar, John Kang, Ruxian Lin…·Joanna Melia

This study shows that a ZIP8 mutation causes aberrant N-glycosylation in Crohn's disease, which can be treated with N-acetylglucosamine supplementation.

DOI 10.1101/2024.06.28.601207

mousehuman

𝕏 PostBluesky