Author

Ritu M Dave

Washington University in St. LouisORCID 0000-0002-5533-7984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Antonina I FrolovaiD· 2 shared Kaci T. MitchumiD· 2 shared Alana Aristimuno Millan· 1 shared Cailin R. GonyeaiD· 1 shared Jordan L RichiD· 1 shared Karla Ortega-SandovaliD· 1 shared Kevin K. PriftiiD· 1 shared Magdaleena Naemi MbadhiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Antonina I FrolovaORCID

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2 papers

Recent·Most cited

Metabolic Flexibility and Energy Substrate Utilization Regulate Contractility in the Human Myometrium

Kevin K. Prifti, Ritu M Dave, Kaci T. Mitchum, Jordan L Rich, Ruth M. Gill, Magdaleena Naemi Mbadhi, Antonina I Frolova

This study investigates how metabolic flexibility and energy substrate utilization affect myometrial contractility in human cells, finding a shift from oxidative phosphorylation to glycolysis during oxytocin-induced contractions.

iScience · Jun 1, 2026Peer-reviewedCell Biology

EMMIs: Engineered Myometrial Microtissues for Direct Quantification of Oxytocin-Induced Contractility

Karla Ortega-Sandoval, Ritu M Dave, Cailin R. Gonyea, Kaci T. Mitchum, Alana Aristimuno Millan, Shriya Suryakumar, Antonina I Frolova, Shreya Artha Raghavan

This paper introduces EMMIs, engineered myometrial microtissues, to directly measure oxytocin-induced contractility and show that prolonged oxytocin exposure reduces contractile force.

bioRxiv · Apr 30, 2026 · PreprintBioengineering