Molecular BiologyNucleic Acids ResearchPeer-reviewed
CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex
Jennifer V. Gerbracht, Volker Boehm, Thiago Britto‐Borges…·Niels H. Gehring
This study shows that CASC3 enhances NMD by linking the EJC to the NMD machinery, leading to increased degradation of NMD-targeted mRNAs.
59 citations